Where immunology meets innovation: explore the Mackay Lab's pioneering discoveries.

At the Mackay Lab, we study memory T cell responses, exploring ways to harness these cells to develop new treatments for disease.

Our breakthrough research allowed us to understand a newly discovered type of immune cell called the tissue-resident memory T cell (or TRM for short).

Led by Professor Laura Mackay, an internationally recognised immunologist at The Doherty Institute, our team employs cutting-edge technologies to drive innovation in our work.

 

Read about how we’re understanding TRM to pioneer new treatments against infection, autoimmune conditions, and cancer.

Our Research

Finding the blueprint for memory T cell development

We’re exploring the intrinsic mechanisms governing memory T cell development across tissues, paving the way for enhanced immunity.

How memory T cells are shaped by their environment

We’re deciphering the environmental cues around T cells and discovering new pathways to revolutionise future vaccines and immunotherapies.

Harnessing protective immune cells for cancer immunotherapy

We’re investigating tumour-resident T cells, leveraging their therapeutic application to create the cancer treatments of tomorrow.

Unravelling the diversity and function of skin-resident T cells

We’re unravelling the role of T cells in the skin to pioneer new approaches to cure autoimmune conditions like psoriasis, alopecia areata, and vitiligo.

Latest News

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What is Pathology immunology?

When health conditions worsen to emergency status, portions of immune system organs, including the thymus, spleen, bone marrow, lymph nodes, and other lymphatic tissues, can ...
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MRSA,_Ingestion_by_Neutrophil

What is Clinical immunology?

When health conditions worsen to emergency status, portions of immune system organs, including the thymus, spleen, bone marrow, lymph nodes, and other lymphatic tissues, can ...
Read More →
MRSA,_Ingestion_by_Neutrophil

Clinical and pathology immunology

When health conditions worsen to emergency status, portions of immune system organs, including the thymus, spleen, bone marrow, lymph nodes, and other lymphatic tissues, can ...
Read More →

Our Technologies

CRISPR/Cas9 Gene editing

Multiomic single-cell technologies

Intravital imaging

Lineage tracing

Mouse/human models

Immunological assays