Where immunology meets innovation: explore the Mackay Lab's pioneering discoveries.
At the Mackay Lab, we study memory T cell responses, exploring ways to harness these cells to develop new treatments for disease.
Our breakthrough research allowed us to understand a newly discovered type of immune cell called the tissue-resident memory T cell (or TRM for short).
Led by Professor Laura Mackay, an internationally recognised immunologist at The Doherty Institute, our team employs cutting-edge technologies to drive innovation in our work.
Read about how we’re understanding TRM to pioneer new treatments against infection, autoimmune conditions, and cancer.
Our Research
Finding the blueprint for memory T cell development
We’re exploring the intrinsic mechanisms governing memory T cell development across tissues, paving the way for enhanced immunity.
How memory T cells are shaped by their environment
We’re deciphering the environmental cues around T cells and discovering new pathways to revolutionise future vaccines and immunotherapies.
Harnessing protective immune cells for cancer immunotherapy
We’re investigating tumour-resident T cells, leveraging their therapeutic application to create the cancer treatments of tomorrow.
Unravelling the diversity and function of skin-resident T cells
We’re unravelling the role of T cells in the skin to pioneer new approaches to cure autoimmune conditions like psoriasis, alopecia areata, and vitiligo.
Latest News
What is Pathology immunology?
What is Clinical immunology?
Clinical and pathology immunology
Our Technologies
CRISPR/Cas9 Gene editing
Multiomic single-cell technologies
Intravital imaging
Lineage tracing
Mouse/human models

